XBI holdings
What SPDR Biotech (XBI) holds: its top holdings by weight and its sector weights.
XBI top holdings
| Holding | Weight |
|---|---|
| MRNA Moderna | 2.36% |
| TWST Twist Bioscience | 1.98% |
| NTRA Natera | 1.89% |
| HALO Halozyme | 1.75% |
| BIIB Biogen | 1.70% |
| AMGN Amgen | 1.69% |
| UTHR United Therapeutics | 1.68% |
| ABBV AbbVie | 1.66% |
| SYRE Spyre Therapeutics | 1.63% |
| GILD Gilead | 1.63% |
| EXEL Exelixis | 1.63% |
| TGTX TG Therapeutics | 1.52% |
| ORKA Oruka Therapeutics | 1.52% |
| GRAL GRAIL | 1.51% |
| VRTX Vertex | 1.49% |
| REGN Regeneron | 1.45% |
| ALKS Alkermes | 1.43% |
| CRSP CRISPR Therapeutics | 1.43% |
| PTGX Protagonist Therapeutics | 1.42% |
| PTCT PTC Therapeutics | 1.37% |
| NBIX Neurocrine Biosciences | 1.35% |
| KRYS Krystal Biotech | 1.34% |
| BBIO BridgeBio Pharma | 1.33% |
| INCY Incyte | 1.33% |
| RVMD Revolution Medicines | 1.31% |
| ROIV Roivant Sciences | 1.29% |
| BMRN BioMarin | 1.28% |
| KYMR Kymera Therapeutics | 1.27% |
| KOD Kodiak Sciences | 1.25% |
| INSM Insmed | 1.24% |
| CYTK Cytokinetics | 1.23% |
| ERAS Erasca | 1.22% |
| COGT Cogent Biosciences | 1.21% |
| PCVX Vaxcyte | 1.21% |
| PRAX PRAXIS PRECISION MEDICINES I | 1.20% |
| VCYT Veracyte | 1.18% |
| IONS Ionis Pharmaceuticals | 1.14% |
| MDGL Madrigal Pharma | 1.13% |
| DNTH Dianthus Therapeutics | 1.11% |
| TVTX Travere Therapeutics | 1.10% |
| RYTM Rhythm Pharmaceuticals | 1.07% |
| ARWR Arrowhead | 1.05% |
| IOVA Iovance | 1.04% |
| MIRM Mirum Pharmaceuticals | 1.03% |
| IBRX ImmunityBio | 0.99% |
| ALNY Alnylam | 0.97% |
| BEAM Beam Therapeutics | 0.96% |
| CGON CG Oncology | 0.95% |
| ARQT Arcutis | 0.94% |
| RLAY Relay Therapeutics | 0.92% |
XBI sector weights
| Sector | Weight |
|---|---|
| Healthcare | 99.28% |
| Financial Services | 0.72% |
- XBI's biggest holdings: MRNA 2.36%, TWST 1.98%, NTRA 1.89%, HALO 1.75%, BIIB 1.70%.
Updated 2026-11-02 18:34 UTC